eF-site ID 3fbc-A
PDB Code 3fbc
Chain A

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Title Crystal structure of the Mimivirus NDK N62L-R107G double mutant complexed with dTDP
Classification TRANSFERASE
Compound Nucleoside diphosphate kinase
Source (NDK_MIMIV)
Sequence A:  GLQRTLVLIKPDAFERSLVAEIMGRIEKKNFKIVSMKFWS
KAPRNLIEQHYKEHSEQSYFNDLCDFMVSGPIISIVYEGT
DAISKIRRLQGNILTPGTIRGDLANDIGENLIHASDSEDS
AVDEISIWFPE
Description


Functional site

1) chain A
residue 86
type
sequence R
description BINDING SITE FOR RESIDUE MG A 160
source : AC1

2) chain A
residue 115
type
sequence D
description BINDING SITE FOR RESIDUE MG A 160
source : AC1

3) chain A
residue 9
type
sequence K
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

4) chain A
residue 53
type
sequence H
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

5) chain A
residue 58
type
sequence Y
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

6) chain A
residue 62
type
sequence L
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

7) chain A
residue 86
type
sequence R
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

8) chain A
residue 99
type
sequence R
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

9) chain A
residue 106
type
sequence I
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

10) chain A
residue 107
type
sequence G
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

11) chain A
residue 109
type
sequence N
description BINDING SITE FOR RESIDUE TYD A 138
source : AC2

12) chain A
residue 90
type
sequence G
description BINDING SITE FOR RESIDUE PO4 A 139
source : AC3

13) chain A
residue 91
type
sequence N
description BINDING SITE FOR RESIDUE PO4 A 139
source : AC3

14) chain A
residue 92
type
sequence I
description BINDING SITE FOR RESIDUE PO4 A 139
source : AC3

15) chain A
residue 99
type
sequence R
description BINDING SITE FOR RESIDUE PO4 A 139
source : AC3

16) chain A
residue 109
type
sequence N
description BINDING SITE FOR RESIDUE PO4 A 139
source : AC3

17) chain A
residue 109-117
type prosite
sequence NLIHASDSE
description NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NliHASDSE
source prosite : PS00469

18) chain A
residue 9
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI2

19) chain A
residue 58
type BINDING
sequence Y
description
source Swiss-Prot : SWS_FT_FI2

20) chain A
residue 86
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

21) chain A
residue 99
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

22) chain A
residue 109
type BINDING
sequence N
description
source Swiss-Prot : SWS_FT_FI2

23) chain A
residue 112
type ACT_SITE
sequence H
description Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU10030
source Swiss-Prot : SWS_FT_FI1


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