eF-site ID 3fa6-AB PDB Code 3fa6 Chain A, B click to enlarge Title Crystal structure of the R132K:Y134F:R111L:L121D:T54V mutant of cellular retinoic acid-binding protein II complexed with C15-aldehyde (a retinal analog) at 1.54 angstrom resolution Classification TRANSPORT PROTEIN Compound Cellular retinoic acid-binding protein 2 Source null (RABP2_HUMAN) Sequence A:  PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPA VEIKQEGDTFYIKVSTTVRTTEINFKVGEEFEEQTVDGRP CKSLVKWESENKMVCEQKLLKGEGPKTSWTLELTNDGELI DTMTADDVVCTKVFVRE B:  PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPA VEIKQEGDTFYIKVSTTVRTTEINFKVGEEFEEQTVDGRP CKSLVKWESENKMVCEQKLLKGEGPKTSWTLELTNDGELI DTMTADDVVCTKVFVRE Description Functional site 1) chain A residue 36 type sequence A description BINDING SITE FOR RESIDUE LSR A 138 source : AC1 2) chain A residue 63 type sequence I description BINDING SITE FOR RESIDUE LSR A 138 source : AC1 3) chain A residue 121 type sequence D description BINDING SITE FOR RESIDUE LSR A 138 source : AC1 4) chain A residue 123 type sequence M description BINDING SITE FOR RESIDUE LSR A 138 source : AC1 5) chain A residue 132 type sequence K description BINDING SITE FOR RESIDUE LSR A 138 source : AC1 6) chain B residue 109 type sequence W description BINDING SITE FOR RESIDUE LSR B 138 source : AC2 7) chain B residue 121 type sequence D description BINDING SITE FOR RESIDUE LSR B 138 source : AC2 8) chain B residue 123 type sequence M description BINDING SITE FOR RESIDUE LSR B 138 source : AC2 9) chain B residue 132 type sequence K description BINDING SITE FOR RESIDUE LSR B 138 source : AC2 10) chain B residue 132 type BINDING sequence K description BINDING => ECO:0000269|PubMed:16979656, ECO:0007744|PDB:2FR3 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 132 type BINDING sequence K description BINDING => ECO:0000269|PubMed:16979656, ECO:0007744|PDB:2FR3 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 5-22 type prosite sequence GNWKIIRSENFEELLKVL description FABP Cytosolic fatty-acid binding proteins signature. GNWkIirSeNFEeLLKVL source prosite : PS00214 13) chain A residue 101 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:21998312 source Swiss-Prot : SWS_FT_FI2 14) chain B residue 101 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:21998312 source Swiss-Prot : SWS_FT_FI2

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