eF-site ID 3f8a-A
PDB Code 3f8a
Chain A

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Title Crystal Structure of the R132K:R111L:L121E:R59W Mutant of Cellular Retinoic Acid-Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.95 Angstrom resolution.
Classification TRANSPORT PROTEIN
Compound Cellular retinoic acid-binding protein 2
Source Homo sapiens (Human) (RABP2_HUMAN)
Sequence A:  PNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPA
VEIKQEGDTFYIKTSTTVWTTEINFKVGEEFEEQTVDGRP
CKSLVKWESENKMVCEQKLLKGEGPKTSWTLELTNDGELI
ETMTADDVVCTKVYVRE
Description


Functional site

1) chain A
residue 54
type
sequence T
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

2) chain A
residue 63
type
sequence I
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

3) chain A
residue 73
type
sequence E
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

4) chain A
residue 109
type
sequence W
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

5) chain A
residue 121
type
sequence E
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

6) chain A
residue 123
type
sequence M
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

7) chain A
residue 132
type
sequence K
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

8) chain A
residue 134
type
sequence Y
description BINDING SITE FOR RESIDUE B3P A 138
source : AC1

9) chain A
residue 15
type
sequence F
description BINDING SITE FOR RESIDUE LSR A 139
source : AC2

10) chain A
residue 32
type
sequence A
description BINDING SITE FOR RESIDUE LSR A 139
source : AC2

11) chain A
residue 56
type
sequence T
description BINDING SITE FOR RESIDUE LSR A 139
source : AC2

12) chain A
residue 132
type
sequence K
description BINDING SITE FOR RESIDUE LSR A 139
source : AC2

13) chain A
residue 132
type BINDING
sequence K
description BINDING => ECO:0000269|PubMed:16979656, ECO:0007744|PDB:2FR3
source Swiss-Prot : SWS_FT_FI1

14) chain A
residue 101
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:21998312
source Swiss-Prot : SWS_FT_FI2

15) chain A
residue 5-22
type prosite
sequence GNWKIIRSENFEELLKVL
description FABP Cytosolic fatty-acid binding proteins signature. GNWkIirSeNFEeLLKVL
source prosite : PS00214


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