|
|
eF-site ID
|
3eze-AB |
|
PDB Code
|
3eze |
|
Chain
|
A, B |
|
click to enlarge
|
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Title
|
COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE |
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Classification
|
TRANSFERASE |
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Compound
|
PROTEIN (PHOSPHOTRANSFERASE SYSTEM, ENZYME I) |
|
Source
|
Escherichia coli (strain K12) (PTHP_ECOLI) |
|
|
Sequence
|
A: |
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEV
ERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL
EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDD
EYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELP
AIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR
AVQEQVASE
|
| B: |
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGK
SASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKL
MAELE
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
189 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE PO3 B 600
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
315 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE PO3 B 600
|
| source |
: AC1
|
|
|
3)
|
chain |
B |
| residue |
316 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE PO3 B 600
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
189 |
| type |
catalytic |
| sequence |
H
|
| description |
920
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
B |
| residue |
315 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00681, ECO:0000269|PubMed:2261470
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
184-195 |
| type |
prosite |
| sequence |
GGRTSHTSIMAR
|
| description |
PEP_ENZYMES_PHOS_SITE PEP-utilizing enzymes phosphorylation site signature. GGrTsHTSIMAR
|
| source |
prosite : PS00370
|
|
|
7)
|
chain |
B |
| residue |
313-320 |
| type |
prosite |
| sequence |
GLHTRPAA
|
| description |
PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GLHTRPAA
|
| source |
prosite : PS00369
|
|
|
8)
|
chain |
B |
| residue |
339-354 |
| type |
prosite |
| sequence |
GKSASAKSLFKLQTLG
|
| description |
PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKsASaKSLFKLQtLG
|
| source |
prosite : PS00589
|
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|
|