eF-site ID 3exx-ABCD PDB Code 3exx Chain A, B, C, D click to enlarge Title Structure of the T6 human insulin derivative with nickel at 1.35 A resolution Classification HORMONE Compound Insulin A chain Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  GIVEQCCTSICSLYQLENYCN B:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT C:  GIVEQCCTSICSLYQLENYCN D:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT Description Functional site 1) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE NI B 31 source : AC1 2) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE NI D 31 source : AC2 3) chain C residue 2 type sequence I description BINDING SITE FOR RESIDUE NA D 32 source : AC3 4) chain D residue 25 type sequence F description BINDING SITE FOR RESIDUE NA D 32 source : AC3 5) chain D residue 26 type sequence Y description BINDING SITE FOR RESIDUE NA D 32 source : AC3 6) chain D residue 27 type sequence T description BINDING SITE FOR RESIDUE NA D 32 source : AC3 7) chain A residue 12 type sequence S description BINDING SITE FOR RESIDUE NA B 32 source : AC4 8) chain A residue 13 type sequence L description BINDING SITE FOR RESIDUE NA B 32 source : AC4 9) chain B residue 1 type sequence F description BINDING SITE FOR RESIDUE NA B 32 source : AC4 10) chain B residue 2 type sequence V description BINDING SITE FOR RESIDUE NA B 32 source : AC4 11) chain A residue 6-20 type prosite sequence CCTSICSLYQLENYC description INSULIN Insulin family signature. CCTSiCSlyqLenyC source prosite : PS00262

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