eF-site ID 3est-A PDB Code 3est Chain A click to enlarge Title STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION Classification HYDROLASE(SERINE PROTEINASE) Compound PORCINE PANCREATIC ELASTASE Source Sus scrofa (Pig) (ELA1_PIG) Sequence A:  VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWV MTAAHCVDRELTFRVVVGEHNLNQNNGTEQYVGVQKIVVH PYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSS SSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQY AVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN Description (1)  NATIVE ELASTASE (E.C.3.4.21.11) Functional site 1) chain A residue 57 type sequence H description catalytic site source : CAT 2) chain A residue 102 type sequence D description catalytic site source : CAT 3) chain A residue 195 type sequence S description catalytic site source : CAT 4) chain A residue 214 type sequence S description catalytic site source : CAT 5) chain A residue 70 type sequence E description BINDING SITE FOR RESIDUE CA A 280 source : AC1 6) chain A residue 72 type sequence N description BINDING SITE FOR RESIDUE CA A 280 source : AC1 7) chain A residue 75 type sequence Q description BINDING SITE FOR RESIDUE CA A 280 source : AC1 8) chain A residue 77 type sequence N description BINDING SITE FOR RESIDUE CA A 280 source : AC1 9) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE CA A 280 source : AC1 10) chain A residue 127 type sequence G description BINDING SITE FOR RESIDUE SO4 A 290 source : AC2 11) chain A residue 230 type sequence R description BINDING SITE FOR RESIDUE SO4 A 290 source : AC2 12) chain A residue 57 type sequence H description BINDING SITE FOR RESIDUE SO4 A 295 source : AC3 13) chain A residue 192 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 295 source : AC3 14) chain A residue 193 type sequence G description BINDING SITE FOR RESIDUE SO4 A 295 source : AC3 15) chain A residue 195 type sequence S description BINDING SITE FOR RESIDUE SO4 A 295 source : AC3 16) chain A residue 57 type ACT_SITE sequence H description Charge relay system => ECO:0000269|PubMed:4578945, ECO:0000269|PubMed:5415110 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 102 type ACT_SITE sequence D description Charge relay system => ECO:0000269|PubMed:5415110 source Swiss-Prot : SWS_FT_FI2 18) chain A residue 195 type ACT_SITE sequence S description Charge relay system => ECO:0000269|PubMed:5415110 source Swiss-Prot : SWS_FT_FI2 19) chain A residue 53-58 type prosite sequence MTAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MTAAHC source prosite : PS00134 20) chain A residue 189-200 type prosite sequence SGCQGDSGGPLH description TRYPSIN_SER Serine proteases, trypsin family, serine active site. SGcqGDSGGPLH source prosite : PS00135 21) chain A residue 70 type BINDING sequence E description BINDING => ECO:0000269|PubMed:7656008, ECO:0007744|PDB:1ELA, ECO:0007744|PDB:1ELB, ECO:0007744|PDB:1ELC source Swiss-Prot : SWS_FT_FI3 22) chain A residue 72 type BINDING sequence N description BINDING => ECO:0000269|PubMed:7656008, ECO:0007744|PDB:1ELA, ECO:0007744|PDB:1ELB, ECO:0007744|PDB:1ELC source Swiss-Prot : SWS_FT_FI3 23) chain A residue 75 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:7656008, ECO:0007744|PDB:1ELA, ECO:0007744|PDB:1ELB, ECO:0007744|PDB:1ELC source Swiss-Prot : SWS_FT_FI3 24) chain A residue 80 type BINDING sequence E description BINDING => ECO:0000269|PubMed:7656008, ECO:0007744|PDB:1ELA, ECO:0007744|PDB:1ELB, ECO:0007744|PDB:1ELC source Swiss-Prot : SWS_FT_FI3

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