eF-site ID 3eq1-B PDB Code 3eq1 Chain B click to enlarge Title The Crystal Structure of Human Porphobilinogen Deaminase at 2.8A resolution Classification TRANSFERASE Compound Porphobilinogen deaminase Source Homo sapiens (Human) (HEM3_HUMAN) Sequence B:  RVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAFTK ELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENP HDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFP HLEFRSIQGNLNTRLRKLDEQQEFSAIILATAGLQRMGWH NRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLH DPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLT GGVWSLDGSDSIQETMQATIHVPQHEDDPQLVGITARNIP RGPQLAAQNLGISLANLLLSKGAKNILDVARQ Description Functional site 1) chain B residue 96 type sequence S description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 2) chain B residue 98 type sequence K description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 3) chain B residue 99 type sequence D description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 4) chain B residue 146 type sequence S description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 5) chain B residue 147 type sequence S description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 6) chain B residue 149 type sequence R description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 7) chain B residue 150 type sequence R description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 8) chain B residue 173 type sequence R description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 9) chain B residue 188 type sequence L description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 10) chain B residue 189 type sequence A description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 11) chain B residue 195 type sequence R description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 12) chain B residue 218 type sequence G description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 13) chain B residue 261 type sequence C description BINDING SITE FOR RESIDUE DPM B 401 source : AC2 14) chain B residue 26 type sequence R description BINDING SITE FOR RESIDUE SO4 B 362 source : AC6 15) chain B residue 28 type sequence S description BINDING SITE FOR RESIDUE SO4 B 362 source : AC6 16) chain B residue 169 type sequence N description BINDING SITE FOR RESIDUE SO4 B 362 source : AC6 17) chain B residue 120 type sequence H description BINDING SITE FOR RESIDUE SO4 B 363 source : AC7 18) chain B residue 207 type sequence H description BINDING SITE FOR RESIDUE SO4 B 363 source : AC7 19) chain B residue 208 type sequence P description BINDING SITE FOR RESIDUE SO4 B 363 source : AC7 20) chain B residue 268 type sequence H description BINDING SITE FOR RESIDUE SO4 B 363 source : AC7 21) chain B residue 119 type sequence P description BINDING SITE FOR RESIDUE SO4 B 364 source : AC8 22) chain B residue 246 type sequence R description BINDING SITE FOR RESIDUE SO4 B 364 source : AC8 23) chain B residue 147 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 24) chain B residue 261 type MOD_RES sequence C description S-(dipyrrolylmethanemethyl)cysteine => ECO:0000269|PubMed:18936296 source Swiss-Prot : SWS_FT_FI4

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