eF-site ID 3eov-B PDB Code 3eov Chain B click to enlarge Title Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A Classification ISOMERASE/IMMUNOSUPPRESSANT Compound PEPTIDYL-PROLYL CIS-TRANS ISOMERASE Source Leishmania donovani (NOR00033) Sequence B:  EPEVTAKVYFDVMIDSEPLGRITIGLFGKDAPLTTENFRQ LCTGEHGFGYKDSIFHRVIQNFMIQGGDFTNFDGTGGKSI YGEKFADENLNVKHFVGALSMANAGPNTNGSQFFITTAPT PWLDGRHVVFGKVLDGMDVVLRIEKTKTNSHDRPVKPVKI VASGEL Description Functional site 1) chain B residue 127 type sequence P description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 2) chain B residue 143 type sequence W description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 3) chain B residue 147 type sequence R description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 4) chain B residue 78 type sequence R description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 5) chain B residue 83 type sequence F description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 6) chain B residue 86 type sequence Q description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 7) chain B residue 95 type sequence G description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 8) chain B residue 123 type sequence A description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 9) chain B residue 124 type sequence N description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 10) chain B residue 133 type sequence Q description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 11) chain B residue 135 type sequence F description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 12) chain B residue 143 type sequence W description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2 13) chain B residue 148 type sequence H description BINDING SITE FOR CHAIN D OF CYCLOSPORIN A source : AC2

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