|
eF-site ID
|
3eh5-A |
PDB Code
|
3eh5 |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus |
Classification
|
OXIDOREDUCTASE |
Compound
|
Cytochrome c oxidase subunit 1 |
Source
|
(COXA_THET8) |
|
Sequence
|
A: |
SEISRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALN
YGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNAIVFTQLFA
QAIMVYLPARELNMRPNMGLMWLSWWMAFIGLVVAALPLL
ANEATVLYTFYPPLKGHWAFYLGASVFVLSTWVSIYIVLD
LWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAV
LFLLPWSFGLVEGVDPLVARTLFWWTGHPIVYFWLLPAYA
IIYTILPKQAGGRLVSDPMARLAFLLFLLLSTPVGFHHQF
ADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGR
LRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGIV
NASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLL
PNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLL
NVPRRAYIAQVPDAYPHAAVPMVFNVLAGIVLLVALLLFI
YGLFSVLLSRERKPELAEAPLPFAEVISGPEDRRLVLAMD
RIGFWFAVAAILVVLAYGPTLVQLFGHLNPVPGWRLW
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
384 |
type |
catalytic |
sequence |
H
|
description |
735
|
source |
MCSA : MCSA1
|
|
2)
|
chain |
A |
residue |
385 |
type |
catalytic |
sequence |
F
|
description |
735
|
source |
MCSA : MCSA1
|
|
3)
|
chain |
A |
residue |
386 |
type |
catalytic |
sequence |
H
|
description |
735
|
source |
MCSA : MCSA1
|
|
4)
|
chain |
A |
residue |
449 |
type |
catalytic |
sequence |
R
|
description |
735
|
source |
MCSA : MCSA1
|
|
5)
|
chain |
A |
residue |
450 |
type |
catalytic |
sequence |
R
|
description |
735
|
source |
MCSA : MCSA1
|
|
6)
|
chain |
A |
residue |
229-283 |
type |
prosite |
sequence |
WWTGHPIVYFWLLPAYAIIYTILPKQAGGRLVSDPMARLA
FLLFLLLSTPVGFHH
|
description |
COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WWTGHPiVyfwllpayaiiytilpkqaggrlvsdpmarlafllflllstpvgf..HH
|
source |
prosite : PS00077
|
|
7)
|
chain |
A |
residue |
282 |
type |
BINDING |
sequence |
H
|
description |
BINDING => ECO:0000305
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
8)
|
chain |
A |
residue |
283 |
type |
BINDING |
sequence |
H
|
description |
BINDING => ECO:0000305
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
9)
|
chain |
A |
residue |
233 |
type |
CROSSLNK |
sequence |
H
|
description |
1'-histidyl-3'-tyrosine (His-Tyr)
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
10)
|
chain |
A |
residue |
237 |
type |
CROSSLNK |
sequence |
Y
|
description |
1'-histidyl-3'-tyrosine (His-Tyr)
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
11)
|
chain |
A |
residue |
385-405 |
type |
TRANSMEM |
sequence |
FHLQVASLVTLTAMGSLYWLL
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
12)
|
chain |
A |
residue |
420-440 |
type |
TRANSMEM |
sequence |
LGLAVVWLWFLGMMIMAVGLH
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
13)
|
chain |
A |
residue |
471-491 |
type |
TRANSMEM |
sequence |
VLAGIVLLVALLLFIYGLFSV
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
14)
|
chain |
A |
residue |
527-547 |
type |
TRANSMEM |
sequence |
IGFWFAVAAILVVLAYGPTLV
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
15)
|
chain |
A |
residue |
74-94 |
type |
TRANSMEM |
sequence |
VLNAIVFTQLFAQAIMVYLPA
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
16)
|
chain |
A |
residue |
105-125 |
type |
TRANSMEM |
sequence |
LMWLSWWMAFIGLVVAALPLL
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
17)
|
chain |
A |
residue |
144-164 |
type |
TRANSMEM |
sequence |
AFYLGASVFVLSTWVSIYIVL
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
18)
|
chain |
A |
residue |
187-207 |
type |
TRANSMEM |
sequence |
VVFWLMWFLASLGLVLEAVLF
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
19)
|
chain |
A |
residue |
227-247 |
type |
TRANSMEM |
sequence |
LFWWTGHPIVYFWLLPAYAII
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
20)
|
chain |
A |
residue |
267-287 |
type |
TRANSMEM |
sequence |
LAFLLFLLLSTPVGFHHQFAD
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
21)
|
chain |
A |
residue |
300-320 |
type |
TRANSMEM |
sequence |
VLTLFVAVPSLMTAFTVAASL
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
22)
|
chain |
A |
residue |
345-365 |
type |
TRANSMEM |
sequence |
AFVAPVLGLLGFIPGGAGGIV
|
description |
Helical
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
23)
|
chain |
A |
residue |
384 |
type |
TOPO_DOM |
sequence |
H
|
description |
Periplasmic
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
24)
|
chain |
A |
residue |
386 |
type |
TOPO_DOM |
sequence |
H
|
description |
Periplasmic
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|