|
|
eF-site ID
|
3edx-F |
|
PDB Code
|
3edx |
|
Chain
|
F |
|
click to enlarge
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|
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Title
|
Crystal structure of the W215A/E217A mutant of murine thrombin |
|
Classification
|
HYDROLASE |
|
Compound
|
Thrombin light chain |
|
Source
|
(THRB_MOUSE) |
|
|
Sequence
|
F: |
IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLT
AAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISM
LEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL
PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVL
QVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDA
CEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRKGKYGFY
THVFRLKRWIQKVIDQFG
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
F |
| residue |
57 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Charge relay system => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
F |
| residue |
102 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Charge relay system => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
F |
| residue |
195 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Charge relay system => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
F |
| residue |
60 |
| type |
CARBOHYD |
| sequence |
L
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
F |
| residue |
186 |
| type |
CARBOHYD |
| sequence |
V
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|