eF-site ID 3ecr-B PDB Code 3ecr Chain B click to enlarge Title Structure of human porphobilinogen deaminase Classification TRANSFERASE Compound Porphobilinogen deaminase Source Homo sapiens (Human) (HEM3_HUMAN) Sequence B:  RVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMKI GEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIG AICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRA AQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATA GLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDI LDLVGVLHDPETLLRCIAERAFLRHLECSVPVAVHTAMKD GQLYLTGGVWSLDGSDSIQETMQATIHPQLVGITARNIPR GPQLAAQNLGISLANLLLSKGAKNILDVAR Description Functional site 1) chain B residue 74 type sequence I description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 2) chain B residue 99 type sequence S description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 3) chain B residue 101 type sequence K description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 4) chain B residue 102 type sequence D description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 5) chain B residue 149 type sequence S description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 6) chain B residue 150 type sequence S description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 7) chain B residue 152 type sequence R description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 8) chain B residue 153 type sequence R description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 9) chain B residue 176 type sequence R description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 10) chain B residue 191 type sequence L description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 11) chain B residue 192 type sequence A description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 12) chain B residue 220 type sequence Q description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 13) chain B residue 221 type sequence G description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 14) chain B residue 264 type sequence C description BINDING SITE FOR RESIDUE DPM B 365 source : AC2 15) chain B residue 150 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 16) chain B residue 77 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P22907 source Swiss-Prot : SWS_FT_FI3 17) chain B residue 264 type MOD_RES sequence C description S-(dipyrrolylmethanemethyl)cysteine => ECO:0000269|PubMed:18936296 source Swiss-Prot : SWS_FT_FI4

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