eF-site ID 3ecr-A PDB Code 3ecr Chain A click to enlarge Title Structure of human porphobilinogen deaminase Classification TRANSFERASE Compound Porphobilinogen deaminase Source Homo sapiens (Human) (HEM3_HUMAN) Sequence A:  MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAML FTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKR ENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQR KFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRM GWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVG VLHDPETLLRCIAERAFLRHLECSVPVAVHTAMKDGQLYL TGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGI TARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVARQ Description Functional site 1) chain A residue 99 type sequence S description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 2) chain A residue 101 type sequence K description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 3) chain A residue 102 type sequence D description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 4) chain A residue 148 type sequence T description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 5) chain A residue 149 type sequence S description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 6) chain A residue 150 type sequence S description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 7) chain A residue 152 type sequence R description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 8) chain A residue 153 type sequence R description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 9) chain A residue 176 type sequence R description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 10) chain A residue 191 type sequence L description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 11) chain A residue 192 type sequence A description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 12) chain A residue 220 type sequence Q description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 13) chain A residue 221 type sequence G description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 14) chain A residue 264 type sequence C description BINDING SITE FOR RESIDUE DPM A 365 source : AC1 15) chain A residue 150 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 16) chain A residue 264 type MOD_RES sequence C description S-(dipyrrolylmethanemethyl)cysteine => ECO:0000269|PubMed:18936296 source Swiss-Prot : SWS_FT_FI4 17) chain A residue 253-269 type prosite sequence ERAFLRHLECSVPVA description PORPHOBILINOGEN_DEAM Porphobilinogen deaminase cofactor-binding site. ERaFlrhLeGGCsVPVA source prosite : PS00533

Display surface Download Links