|
eF-site ID
|
3e8d-D |
PDB Code
|
3e8d |
Chain
|
D |
|
click to enlarge
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|
Title
|
Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors |
Classification
|
TRANSFERASE |
Compound
|
RAC-beta serine/threonine-protein kinase |
Source
|
Homo sapiens (Human) (GSK3B_HUMAN) |
|
Sequence
|
D: |
GRPRTTSFAE
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
D |
residue |
9 |
type |
|
sequence |
S
|
description |
BINDING SITE FOR RESIDUE G98 B 1
|
source |
: AC2
|
|
2)
|
chain |
D |
residue |
9 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine; by PKB/AKT1, RPS6KA3 and SGK3 => ECO:0000269|PubMed:12054501, ECO:0000269|PubMed:16484495, ECO:0000269|PubMed:20937854, ECO:0000269|PubMed:24391509, ECO:0000269|PubMed:25169422, ECO:0000269|PubMed:35606353, ECO:0000269|PubMed:8250835
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
|
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