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eF-site ID
|
3e8d-D |
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PDB Code
|
3e8d |
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Chain
|
D |
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click to enlarge
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Title
|
Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors |
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Classification
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TRANSFERASE |
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Compound
|
RAC-beta serine/threonine-protein kinase |
|
Source
|
null (GSK3B_HUMAN) |
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Sequence
|
D: |
GRPRTTSFAE
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Description
|
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Functional site
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|
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1)
|
chain |
D |
| residue |
9 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE G98 B 1
|
| source |
: AC2
|
|
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2)
|
chain |
D |
| residue |
9 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKB/AKT1, RPS6KA3 and SGK3 => ECO:0000269|PubMed:12054501, ECO:0000269|PubMed:16484495, ECO:0000269|PubMed:20937854, ECO:0000269|PubMed:24391509, ECO:0000269|PubMed:25169422, ECO:0000269|PubMed:8250835
|
| source |
Swiss-Prot : SWS_FT_FI1
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