|
|
eF-site ID
|
3e8d-C |
|
PDB Code
|
3e8d |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors |
|
Classification
|
TRANSFERASE |
|
Compound
|
RAC-beta serine/threonine-protein kinase |
|
Source
|
null (GSK3B_HUMAN) |
|
|
Sequence
|
C: |
GRPRTTSFAE
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
9 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE G98 A 1
|
| source |
: AC1
|
|
|
2)
|
chain |
C |
| residue |
9 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKB/AKT1, RPS6KA3 and SGK3 => ECO:0000269|PubMed:12054501, ECO:0000269|PubMed:16484495, ECO:0000269|PubMed:20937854, ECO:0000269|PubMed:24391509, ECO:0000269|PubMed:25169422, ECO:0000269|PubMed:8250835
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|