eF-site ID 3dzi-B PDB Code 3dzi Chain B click to enlarge Title Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex Classification HYDROLASE Compound ADP-ribosyl cyclase 1 Source Homo sapiens (Human) (CD38_HUMAN) Sequence B:  RWRQTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQS VWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILL WSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFD TSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVV HVMLDGSRSKIFDKDSTFGSVEVHNLQPEKVQTLEAWVIH GGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKF LQCVKNPEDSSC Description Functional site 1) chain B residue 127 type sequence R description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 2) chain B residue 146 type sequence E description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 3) chain B residue 155 type sequence D description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 4) chain B residue 185 type sequence V description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 5) chain B residue 189 type sequence W description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 6) chain B residue 193 type sequence S description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 7) chain B residue 221 type sequence T description BINDING SITE FOR RESIDUE GTP B 302 source : AC1 8) chain B residue 164 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 9) chain B residue 219 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 source Swiss-Prot : SWS_FT_FI4 10) chain B residue 119 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 11) chain B residue 201 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 100 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2 13) chain B residue 209 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2

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