eF-site ID 3dxb-E PDB Code 3dxb Chain E click to enlarge Title Structure of the UHM domain of Puf60 fused to thioredoxin Classification SPLICING, TRANSCRIPTION Compound thioredoxin N-terminally fused to Puf60(UHM) Source Homo sapiens (Human) (PUF60_HUMAN) Sequence E:  KIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPIL DEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFK NGEVAATKVGALSKGQLKEFLDANLAGSAMESTVMVLRNM VDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDA EIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQ ERFDNSDLSA Description Functional site 1) chain E residue 464 type sequence R description BINDING SITE FOR RESIDUE EDO E 557 source : AC2 2) chain E residue 544 type sequence Y description BINDING SITE FOR RESIDUE EDO E 557 source : AC2 3) chain E residue 545 type sequence D description BINDING SITE FOR RESIDUE EDO E 557 source : AC2 4) chain E residue 556 type sequence A description BINDING SITE FOR RESIDUE EDO E 557 source : AC2 5) chain E residue 370 type SITE sequence D description Deprotonates C-terminal active site Cys => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 6) chain E residue 379 type ACT_SITE sequence C description Nucleophile => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 7) chain E residue 376 type ACT_SITE sequence C description Nucleophile => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 8) chain E residue 378 type SITE sequence P description Contributes to redox potential value => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 9) chain E residue 377 type SITE sequence G description Contributes to redox potential value => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 10) chain E residue 413 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250 source Swiss-Prot : SWS_FT_FI4

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