eF-site ID 3dr1-AB PDB Code 3dr1 Chain A, B click to enlarge Title Side-chain fluorine atoms of non-steroidal vitamin D3 analogs stabilize helix 12 of vitamin D receptor Classification GENE REGULATION/TRANSFERASE Compound Vitamin D3 receptor A Source Danio rerio (Zebrafish) (Brachydanio rerio) (NCOA1_HUMAN) Sequence A:  SHMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRL SMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLK SSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAG HTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRP GVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQK LADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV B:  RHKILHRLLQE Description Functional site 1) chain A residue 175 type sequence Y description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 2) chain A residue 179 type sequence Y description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 3) chain A residue 255 type sequence L description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 4) chain A residue 265 type sequence S description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 5) chain A residue 302 type sequence R description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 6) chain A residue 303 type sequence S description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 7) chain A residue 306 type sequence S description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 8) chain A residue 316 type sequence C description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 9) chain A residue 331 type sequence A description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 10) chain A residue 333 type sequence H description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 11) chain A residue 341 type sequence L description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 12) chain A residue 423 type sequence H description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 13) chain A residue 427 type sequence Y description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 14) chain A residue 430 type sequence L description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 15) chain A residue 440 type sequence L description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 16) chain A residue 448 type sequence F description BINDING SITE FOR RESIDUE C5D A 500 source : AC1 17) chain A residue 255 type MOD_RES sequence L description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 299 type MOD_RES sequence I description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 19) chain A residue 333 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 20) chain A residue 423 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1

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