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eF-site ID
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3dpl-C |
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PDB Code
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3dpl |
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Chain
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C |
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click to enlarge
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Title
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Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation. |
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Classification
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LIGASE |
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Compound
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Cullin-5 |
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Source
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Homo sapiens (Human) (RBX1_HUMAN) |
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Sequence
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C: |
ESKCPEELANYCDMLLRKTPLSKKLTSEEIEAKLKEVLKK
LKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWL
REVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNALP
ADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFY
KKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAV
LFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPK
LKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQK
RGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQI
MKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIE
HKYIRRDESDINTFIYMA
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Description
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Functional site
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|
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1)
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chain |
C |
| residue |
753-780 |
| type |
prosite |
| sequence |
IKEQIEWLIEHKYIRRDESDINTFIYMA
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| description |
CULLIN_1 Cullin family signature. IKeqIewLIEHkYIrRdesdintFiYmA
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| source |
prosite : PS01256
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