eF-site ID 3dki-AB PDB Code 3dki Chain A, B click to enlarge Title 2.1 A X-ray structure of CysM (Rv1336) from Mycobacterium tuberculosis an O-phosphoserine dependent cysteine synthase Classification TRANSFERASE Compound Cysteine synthase B Source Mycobacterium tuberculosis (CYSM_MYCTU) Sequence A:  RYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLE DRNPTGSIXDRPAVRMIEQAEADGLLRPGATILEPTSGNT GISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIF SAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHY CGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVAN VKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSV GAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALA AGERADIALVVADAGWKYLSTGAYAGSLDDA B:  HMARYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWA KLEDRNPTGSIXDRPAVRMIEQAEADGLLRPGATILEPTS GNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQ IIFSATAVATAKELAATNPSWVMLYQYGNPANTDSHYCGT GPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKI VAAEPVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIF AGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYL STGAYAGSLDDAETA Description Functional site 1) chain B residue 140 type sequence A description BINDING SITE FOR RESIDUE NA B 324 source : AC1 2) chain B residue 143 type sequence N description BINDING SITE FOR RESIDUE NA B 324 source : AC1 3) chain B residue 146 type sequence W description BINDING SITE FOR RESIDUE NA B 324 source : AC1 4) chain A residue 51 type MOD_RES sequence X description N6-(pyridoxal phosphate)lysine source Swiss-Prot : SWS_FT_FI4 5) chain B residue 51 type MOD_RES sequence X description N6-(pyridoxal phosphate)lysine source Swiss-Prot : SWS_FT_FI4 6) chain A residue 40-58 type prosite sequence KLEDRNPTGSIXDRPAVRM description CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEdrn.PTgSIKdRpAvrM source prosite : PS00901 7) chain A residue 81 type BINDING sequence N description BINDING => ECO:0000269|PubMed:18771296, ECO:0000269|PubMed:18799456, ECO:0000269|PubMed:19101553 source Swiss-Prot : SWS_FT_FI1 8) chain A residue 265 type BINDING sequence S description BINDING => ECO:0000269|PubMed:18771296, ECO:0000269|PubMed:18799456, ECO:0000269|PubMed:19101553 source Swiss-Prot : SWS_FT_FI1 9) chain B residue 81 type BINDING sequence N description BINDING => ECO:0000269|PubMed:18771296, ECO:0000269|PubMed:18799456, ECO:0000269|PubMed:19101553 source Swiss-Prot : SWS_FT_FI1 10) chain B residue 265 type BINDING sequence S description BINDING => ECO:0000269|PubMed:18771296, ECO:0000269|PubMed:18799456, ECO:0000269|PubMed:19101553 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 184 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 12) chain B residue 184 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 13) chain A residue 220 type BINDING sequence R description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI3

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