|
|
eF-site ID
|
3djt-B |
|
PDB Code
|
3djt |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
Crystal structure of transthyretin variant V30M at acidic pH |
|
Classification
|
TRANSPORT PROTEIN |
|
Compound
|
Transthyretin |
|
Source
|
Homo sapiens (Human) (TTHY_HUMAN) |
|
|
Sequence
|
B: |
CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKT
SESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHE
HAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
98 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
2)
|
chain |
B |
| residue |
15 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
54 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
117 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
B |
| residue |
10 |
| type |
MOD_RES |
| sequence |
C
|
| description |
Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
B |
| residue |
42 |
| type |
MOD_RES |
| sequence |
E
|
| description |
4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
B |
| residue |
52 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P02767
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|