eF-site ID 3d45-B PDB Code 3d45 Chain B click to enlarge Title Crystal structure of mouse PARN in complex with m7GpppG Classification HYDROLASE Compound Poly(A)-specific ribonuclease PARN Source Mus musculus (Mouse) (PARN_MOUSE) Sequence B:  GPMEIIRSNFKINLHKVYQAIEEADFFAIDGEFSGISDGP SVTALTSGFDTPEERYQKLKKHSMDFLLFQFGLCAFKYDH TDSKHVTKSFNFYVFPKPFSRSSPDVKFVCQSSSIDFLAS QGFDFNKVFCSGIPYLNQEEERQLRETKEQEELNDAVGFS RVIHAIANSGKLVVGHNMLLDVMHTIHQFYCPLPADLNEF KEMAICVFPRLLDTKLMASTQPFKDIINNTSLAELEKRLK ETPFDPPKVESAEHEAGYDAYITGLCFISMANYLGSKLIE PFFNKLFLMRIPYLNLEGPDLQPKRDHVLHVTFPKEWKTS DLYQLFSAFGNIQISWIDDTSAFVSLSQPEQVQIAVNTSK YAESYRIQTYAEY Description Functional site 1) chain B residue 447 type sequence K description BINDING SITE FOR RESIDUE 7MG B 1152 source : AC3 2) chain B residue 449 type sequence W description BINDING SITE FOR RESIDUE 7MG B 1152 source : AC3 3) chain B residue 450 type sequence K description BINDING SITE FOR RESIDUE 7MG B 1152 source : AC3 4) chain B residue 468 type sequence W description BINDING SITE FOR RESIDUE 7MG B 1152 source : AC3 5) chain B residue 470 type sequence D description BINDING SITE FOR RESIDUE 7MG B 1152 source : AC3 6) chain B residue 471 type sequence D description BINDING SITE FOR RESIDUE 7MG B 1152 source : AC3 7) chain B residue 471 type sequence D description BINDING SITE FOR RESIDUE GDP B 1151 source : AC4 8) chain B residue 28 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 9) chain B residue 30 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 10) chain B residue 285 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 11) chain B residue 375 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 319 type SITE sequence K description Interaction with poly(A) => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI2 13) chain B residue 492 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI3

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