eF-site ID 3d45-A PDB Code 3d45 Chain A click to enlarge Title Crystal structure of mouse PARN in complex with m7GpppG Classification HYDROLASE Compound Poly(A)-specific ribonuclease PARN Source Mus musculus (Mouse) (PARN_MOUSE) Sequence A:  GPMEIIRSNFKINLHKVYQAIEEADFFAIDGEFSGISDSG FDTPEERYQKLKKHSMDFLLFQFGLCAFKYDHTDSKHVTK SFNFYVFPKPFSRSSPDVKFVCQSSSIDFLASQGFDFNKV FCSGIPYLNQEEERQLREQFDEYTKEQEELNDAVGFSRVI HAIANSGKLVVGHNMLLDVMHTIHQFYCPLPADLNEFKEM AICVFPRLLDTKLMASTQPFKDIINNTSLAELEKRLKETP FDPPKVESAEGFPSYDQLHEAGYDAYITGLCFISMANYLG SSARSKLIEPFFNKLFLMRVMDIPYLNLEGPDLQPKRDHV LHVTFPKEWKTSDLYQLFSAFGNIQISWIDDTSAFVSLSQ PEQVQIAVNTSKYAESYRIQTYA Description Functional site 1) chain A residue 319 type sequence K description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 2) chain A residue 333 type sequence N description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 3) chain A residue 447 type sequence K description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 4) chain A residue 449 type sequence W description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 5) chain A residue 450 type sequence K description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 6) chain A residue 451 type sequence T description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 7) chain A residue 468 type sequence W description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 8) chain A residue 470 type sequence D description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 9) chain A residue 471 type sequence D description BINDING SITE FOR RESIDUE 7MG A 651 source : AC1 10) chain A residue 31 type sequence F description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 11) chain A residue 280 type sequence H description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 12) chain A residue 281 type sequence N description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 13) chain A residue 284 type sequence L description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 14) chain A residue 319 type sequence K description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 15) chain A residue 334 type sequence T description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 16) chain A residue 335 type sequence S description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 17) chain A residue 336 type sequence L description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 18) chain A residue 418 type sequence M description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 19) chain A residue 419 type sequence R description BINDING SITE FOR RESIDUE GDP A 652 source : AC2 20) chain A residue 99 type sequence R description BINDING SITE FOR RESIDUE GDP B 1151 source : AC4 21) chain A residue 28 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 30 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 23) chain A residue 285 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 24) chain A residue 375 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI1 25) chain A residue 319 type SITE sequence K description Interaction with poly(A) => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI2 26) chain A residue 492 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O95453 source Swiss-Prot : SWS_FT_FI3

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