eF-site ID 3cs8-A PDB Code 3cs8 Chain A click to enlarge Title Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a Classification NUCLEAR PROTEIN Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PRGC1_HUMAN) Sequence A:  RGGSPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKT TDKSPFVIYDMNSLMMGEDKIPLQEQSKEVAIRIFQGCQF RSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIY TMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPK FEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIE DIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVT EHVQLLQVIKKTETDMSLHPLLQEIYKDL Description Functional site 1) chain A residue 234 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 2) chain A residue 334 type sequence M description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 3) chain A residue 335 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 4) chain A residue 336 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 5) chain A residue 375 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 6) chain A residue 358 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 7) chain A residue 369 type sequence E description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 8) chain A residue 370 type sequence F description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 9) chain A residue 373 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 10) chain A residue 445 type sequence I description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 11) chain A residue 230 type sequence K description BINDING SITE FOR RESIDUE SO4 A 3 source : AC3 12) chain A residue 231 type sequence A description BINDING SITE FOR RESIDUE SO4 A 3 source : AC3 13) chain A residue 234 type sequence R description BINDING SITE FOR RESIDUE SO4 A 3 source : AC3 14) chain A residue 379 type sequence L description BINDING SITE FOR RESIDUE SO4 A 3 source : AC3 15) chain A residue 380 type sequence D description BINDING SITE FOR RESIDUE SO4 A 3 source : AC3 16) chain A residue 204 type sequence G description BINDING SITE FOR RESIDUE SO4 B 1 source : AC4 17) chain A residue 205 type sequence S description BINDING SITE FOR RESIDUE SO4 B 1 source : AC4 18) chain A residue 206 type sequence P description BINDING SITE FOR RESIDUE SO4 B 1 source : AC4 19) chain A residue 281 type sequence I description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 20) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 21) chain A residue 286 type sequence Q description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 22) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 23) chain A residue 341 type sequence I description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 24) chain A residue 364 type sequence M description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 25) chain A residue 367 type sequence K description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 26) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 27) chain A residue 453 type sequence L description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 28) chain A residue 469 type sequence L description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 29) chain A residue 473 type sequence Y description BINDING SITE FOR RESIDUE BRL A 503 source : AC5 30) chain A residue 323 type MOD_RES sequence H description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 31) chain A residue 449 type MOD_RES sequence H description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 473 type MOD_RES sequence Y description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 33) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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