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eF-site ID
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3cjc-A |
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PDB Code
|
3cjc |
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Chain
|
A |
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click to enlarge
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Title
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Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with DNase I and Gelsolin-segment 1 |
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Classification
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Structural protein/Hydrolase |
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Compound
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Actin, alpha skeletal muscle |
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Source
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ORGANISM_COMMON: rabbit; ORGANISM_SCIENTIFIC: Oryctolagus cuniculus; |
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Sequence
|
A: |
DEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRH
QGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWD
DMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMT
QIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVT
HNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSF
VTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYN
SIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITAL
APSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQ
EYDEAGPSIVHR
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Description
|
(1) |
Actin, alpha skeletal muscle, Deoxyribonuclease-1 (E.C.3.1.21.1), Gelsolin
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Functional site
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|
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1)
|
chain |
A |
| residue |
84 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6-methyllysine => ECO:0000250|UniProtKB:P68133
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| source |
Swiss-Prot : SWS_FT_FI6
|
|
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2)
|
chain |
A |
| residue |
177 |
| type |
MOD_RES |
| sequence |
R
|
| description |
ADP-ribosylarginine; by SpvB => ECO:0000305|PubMed:16905096
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| source |
Swiss-Prot : SWS_FT_FI7
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|
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3)
|
chain |
A |
| residue |
53-63 |
| type |
prosite |
| sequence |
YVGDEAQSKRG
|
| description |
ACTINS_1 Actins signature 1. YVGDEAQs.KRG
|
| source |
prosite : PS00406
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|
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4)
|
chain |
A |
| residue |
356-364 |
| type |
prosite |
| sequence |
WITKQEYDE
|
| description |
ACTINS_2 Actins signature 2. WITKqEYDE
|
| source |
prosite : PS00432
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|
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5)
|
chain |
A |
| residue |
104-116 |
| type |
prosite |
| sequence |
LLTEAPLNPKANR
|
| description |
ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
|
| source |
prosite : PS01132
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