eF-site ID 3cf6-R PDB Code 3cf6 Chain R click to enlarge Title Structure of Epac2 in complex with cyclic-AMP and Rap Classification SIGNALING PROTEIN/GTP-BINDING PROTEIN Compound Rap guanine nucleotide exchange factor (GEF) 4 Source null (RAP1B_HUMAN) Sequence R:  EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRK QVQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQ STFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVG KEQGQNLAFLESSAKSKINVNEIFYDLVRQ Description Functional site 1) chain R residue 11 type sequence S description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 2) chain R residue 12 type sequence G description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 3) chain R residue 13 type sequence G description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 4) chain R residue 15 type sequence G description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 5) chain R residue 16 type sequence K description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 6) chain R residue 17 type sequence S description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 7) chain R residue 59 type sequence A description BINDING SITE FOR RESIDUE SO4 R 168 source : AC1 8) chain R residue 10 type BINDING sequence G description BINDING => ECO:0000269|PubMed:18309292, ECO:0000269|PubMed:22577140 source Swiss-Prot : SWS_FT_FI1 9) chain R residue 57 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18309292, ECO:0000269|PubMed:22577140 source Swiss-Prot : SWS_FT_FI1 10) chain R residue 116 type BINDING sequence N description BINDING => ECO:0000269|PubMed:18309292, ECO:0000269|PubMed:22577140 source Swiss-Prot : SWS_FT_FI1 11) chain R residue 147 type BINDING sequence S description BINDING => ECO:0000269|PubMed:18309292, ECO:0000269|PubMed:22577140 source Swiss-Prot : SWS_FT_FI1 12) chain R residue 39 type MOD_RES sequence S description ADP-ribosylserine; by botulinum toxin => ECO:0000305|PubMed:3141412 source Swiss-Prot : SWS_FT_FI2

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