eF-site ID 3bsz-A
PDB Code 3bsz
Chain A

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Title Crystal structure of the transthyretin-retinol binding protein-Fab complex
Classification TRANSPORT PROTEIN/IMMUNE SYSTEM
Compound Transthyretin
Source ORGANISM_COMMON: Human; ORGANISM_SCIENTIFIC: Homo sapiens;
Sequence A:  ESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFAS
GKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISP
FHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP
Description


Functional site

1) chain A
residue 117
type BINDING
sequence S
description BINDING => ECO:0000250|UniProtKB:P27485
source Swiss-Prot : SWS_FT_FI1

2) chain A
residue 98
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329
source Swiss-Prot : SWS_FT_FI5

3) chain A
residue 42
type MOD_RES
sequence E
description 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012
source Swiss-Prot : SWS_FT_FI3

4) chain A
residue 52
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:P02767
source Swiss-Prot : SWS_FT_FI4

5) chain A
residue 15-30
type prosite
sequence KVLDAVRGSPAINVAV
description TRANSTHYRETIN_1 Transthyretin signature 1. KVLDavrGsPAinVaV
source prosite : PS00768

6) chain A
residue 105-117
type prosite
sequence YTIAALLSPYSYS
description TRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPYSYS
source prosite : PS00769


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