eF-site ID 3blx-J PDB Code 3blx Chain J click to enlarge Title Yeast Isocitrate Dehydrogenase (Apo Form) Classification OXIDOREDUCTASE Compound Isocitrate dehydrogenase [NAD] subunit 1 Source null (IDH2_YEAST) Sequence J:  QPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIF SAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVAL KGPLATPRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENV DLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVI RYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSK EYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDI LSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAG QDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASG PENRTGDLAGTATTSSFTEAVIKRL Description Functional site 1) chain J residue 138 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI5 2) chain J residue 312 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI6 3) chain J residue 334 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:17761666 source Swiss-Prot : SWS_FT_FI7 4) chain J residue 252 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P50213 source Swiss-Prot : SWS_FT_FI2 5) chain J residue 248 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P50213 source Swiss-Prot : SWS_FT_FI2 6) chain J residue 142 type SITE sequence Y description Critical for catalysis => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 7) chain J residue 189 type SITE sequence K description Critical for catalysis => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 8) chain J residue 90 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI4 9) chain J residue 104 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 10) chain J residue 114 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 11) chain J residue 135 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 12) chain J residue 222 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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