eF-site ID 3blw-A PDB Code 3blw Chain A click to enlarge Title Yeast Isocitrate Dehydrogenase with Citrate and AMP Bound in the Regulatory Subunits Classification OXIDOREDUCTASE Compound Isocitrate dehydrogenase [NAD] subunit 1 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (IDH2_YEAST) Sequence A:  GRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIK EGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQ LDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLE HESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTA VHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNAS MQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGA NFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLN HLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTN EIINKLSTM Description Functional site 1) chain A residue 83 type sequence T description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 2) chain A residue 92 type sequence S description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 3) chain A residue 94 type sequence N description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 4) chain A residue 95 type sequence V description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 5) chain A residue 98 type sequence R description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 6) chain A residue 129 type sequence R description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 7) chain A residue 136 type sequence F description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 8) chain A residue 241 type sequence T description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 9) chain A residue 274 type sequence R description BINDING SITE FOR RESIDUE FLC A 1001 source : AC1 10) chain A residue 275 type sequence H description BINDING SITE FOR RESIDUE AMP A 2001 source : AC9 11) chain A residue 277 type sequence G description BINDING SITE FOR RESIDUE AMP A 2001 source : AC9 12) chain A residue 286 type sequence A description BINDING SITE FOR RESIDUE AMP A 2001 source : AC9 13) chain A residue 287 type sequence N description BINDING SITE FOR RESIDUE AMP A 2001 source : AC9 14) chain A residue 328 type sequence D description BINDING SITE FOR RESIDUE AMP A 2001 source : AC9 15) chain A residue 237-256 type prosite sequence SMYGTILGNIGAALIGGPGL description IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLYGDIlSDlnSglsaGSLGL source prosite : PS00470

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