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|
eF-site ID
|
3bky-HLP |
|
PDB Code
|
3bky |
|
Chain
|
H, L, P |
|
click to enlarge
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Title
|
Crystal Structure of Chimeric Antibody C2H7 Fab in complex with a CD20 Peptide |
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Classification
|
IMMUNE SYSTEM |
|
Compound
|
the Fab fragment of chimeric 2H7, heavy chain |
|
Source
|
(CD20_HUMAN) |
|
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Sequence
|
H: |
QAYLQQSGAELVRPGASVKMSCKASGYTFTSYNMHWVKQT
PRQGLEWIGAIYPGNGDTSYNQKFKGKATLTVDKSSSTAY
MQLSSLTSEDSAVYFCARVVYYSNSYWYFDVWGTGTTVTV
SAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVT
VSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPKSCD
|
| L: |
QIVLSQSPAILSASPGEKVTMTCRASSSVSYMHWYQQKPG
SSPKPWIYAPSNLASGVPARFSGSGSGTSYSLTISRVEAE
DAATYYCQQWSFNPPTFGAGTKLELKRTVAAPSVFIFPPS
DEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQE
SVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGL
SSPVTKSFNRGEC
|
| P: |
CEPANPSEKNSPSTQYC
|
|
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Description
|
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Functional site
|
|
|
1)
|
chain |
H |
| residue |
203-209 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
L |
| residue |
191-197 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
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