eF-site ID 3bhd-B PDB Code 3bhd Chain B click to enlarge Title Crystal structure of human thiamine triphosphatase (THTPA) Classification HYDROLASE Compound Thiamine triphosphatase Source Homo sapiens (Human) (THTPA_HUMAN) Sequence B:  QGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDT PELSLXQADHWLRRREDSGWELKCPGAAGVLGPHTEYKEL TAEPTIVAQLCKVLRADGLGAGDVAAVLGPLGLQEVASFV TKRSAWKLVLLGADEEEPQLRVDLDTADFGYAVGEVEALV HEEAEVPTALEKIHRLSSXLGVPAQETAPAKLIVYLQRFR PQDYQR Description Functional site 1) chain B residue 9 type sequence E description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 2) chain B residue 11 type sequence K description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 3) chain B residue 39 type sequence Y description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 4) chain B residue 53 type sequence W description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 5) chain B residue 55 type sequence R description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 6) chain B residue 65 type sequence K description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 7) chain B residue 76 type sequence H description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 8) chain B residue 79 type sequence Y description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 9) chain B residue 192 type sequence A description BINDING SITE FOR RESIDUE CIT B 217 source : AC5 10) chain B residue 11 type sequence K description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 11) chain B residue 39 type sequence Y description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 12) chain B residue 55 type sequence R description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 13) chain B residue 57 type sequence R description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 14) chain B residue 65 type sequence K description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 15) chain B residue 125 type sequence R description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 16) chain B residue 157 type sequence E description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 17) chain B residue 192 type sequence A description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 18) chain B residue 193 type sequence K description BINDING SITE FOR RESIDUE CIT B 218 source : AC6 19) chain B residue 34 type sequence T description BINDING SITE FOR RESIDUE GOL B 219 source : AC7 20) chain B residue 58 type sequence E description BINDING SITE FOR RESIDUE GOL B 219 source : AC7 21) chain B residue 31 type sequence Y description BINDING SITE FOR RESIDUE GOL B 220 source : AC8 22) chain B residue 57 type sequence R description BINDING SITE FOR RESIDUE GOL B 220 source : AC8 23) chain B residue 58 type sequence E description BINDING SITE FOR RESIDUE GOL B 220 source : AC8 24) chain B residue 59 type sequence D description BINDING SITE FOR RESIDUE GOL B 220 source : AC8 25) chain B residue 60 type sequence S description BINDING SITE FOR RESIDUE GOL B 220 source : AC8 26) chain B residue 125 type sequence R description BINDING SITE FOR RESIDUE GOL B 220 source : AC8 27) chain B residue 12 type sequence F description BINDING SITE FOR RESIDUE GOL B 221 source : AC9 28) chain B residue 13 type sequence L description BINDING SITE FOR RESIDUE GOL B 221 source : AC9 29) chain B residue 179 type sequence S description BINDING SITE FOR RESIDUE GOL B 221 source : AC9 30) chain B residue 180 type sequence S description BINDING SITE FOR RESIDUE GOL B 221 source : AC9 31) chain B residue 183 type sequence G description BINDING SITE FOR RESIDUE GOL B 221 source : AC9 32) chain B residue 184 type sequence V description BINDING SITE FOR RESIDUE GOL B 221 source : AC9 33) chain B residue 53 type sequence W description BINDING SITE FOR RESIDUE GOL B 222 source : BC1 34) chain B residue 76 type sequence H description BINDING SITE FOR RESIDUE GOL B 222 source : BC1 35) chain B residue 19 type sequence E description BINDING SITE FOR RESIDUE GOL B 223 source : BC2 36) chain B residue 124 type sequence K description BINDING SITE FOR RESIDUE GOL B 223 source : BC2 37) chain B residue 126 type sequence S description BINDING SITE FOR RESIDUE GOL B 223 source : BC2 38) chain B residue 146 type sequence L description BINDING SITE FOR RESIDUE GOL B 223 source : BC2 39) chain B residue 147 type sequence D description BINDING SITE FOR RESIDUE GOL B 223 source : BC2 40) chain B residue 148 type sequence T description BINDING SITE FOR RESIDUE GOL B 223 source : BC2 41) chain B residue 7 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 42) chain B residue 9 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 43) chain B residue 145 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 44) chain B residue 159 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 45) chain B residue 65 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 46) chain B residue 125 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 47) chain B residue 157 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 48) chain B residue 11 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 49) chain B residue 55 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 50) chain B residue 57 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 51) chain B residue 193 type BINDING sequence K description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI3

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