eF-site ID 3bez-ABCD PDB Code 3bez Chain A, B, C, D click to enlarge Title Crystal structure of Escherichia coli Signal peptide peptidase (SppA), SeMet crystals Classification HYDROLASE Compound Protease 4 Source Escherichia coli (strain K12) (SPPA_ECOLI) Sequence A:  RGALLLDISGVIVDKPQENSLFDIVNTIRQAKDDRNITGI VXDLKNFAGGDQPSXQYIGKALKEFRDSGKPVYAVGENYS QGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKL KVSTHVFRVGTYKSAVEPFIRDDXSPAAREADSRWIGELW QNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYA LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDY ALKTPADTGDSIGVVFANGAIXDGEETQGNVGGDTTAAQI RDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAARAAG KPVVVSXGGXAASGGYWISTPANYIVANPSTLTGSIGIFG VITTVENSLDSIGVHTDGVSTSPLADVSITRALPPEAQLX XQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQD AKANGLVDSLGDFDDAVAKAAELAKVKQWHLEY B:  RGALLLDISGVIVDKPQENSLFDIVNTIRQAKDDRNITGI VXDLKNFAGGDQPSXQYIGKALKEFRDSGKPVYAVGENYS QGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKL KVSTHVFRVGTYKSAVEPFIRDDXSPAAREADSRWIGELW QNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYA LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDY ALKTPADTGDSIGVVFANGAIXDGEETQGNVGGDTTAAQI RDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAARAAG KPVVVSXGGXAASGGYWISTPANYIVANPSTLTGSIGIFG VITTVENSLDSIGVHTDGVSTSPLADVSITRALPPEAQLX XQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQD AKANGLVDSLGDFDDAVAKAAELAKVKQWHLEY C:  SRGALLLDISGVIVDKPQENSLFDIVNTIRQAKDDRNITG IVXDLKNFAGGDQPSXQYIGKALKEFRDSGKPVYAVGENY SQGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDK LKVSTHVFRVGTYKSAVEPFIRDDXSPAAREADSRWIGEL WQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKY ALENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYD YALKTPADTGDSIGVVFANGAIXDGEETQGNVGGDTTAAQ IRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAARAA GKPVVVSXGGXAASGGYWISTPANYIVANPSTLTGSIGIF GVITTVENSLDSIGVHTDGVSTSPLADVSITRALPPEAQL XXQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQ DAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYV D:  ASRGALLLDISGVIVDKPDSQENSLFDIVNTIRQAKDDRN ITGIVXDLKNFAGGDQPSXQYIGKALKEFRDSGKPVYAVG ENYSQGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSL LDKLKVSTHVFRVGTYKSAVEPFIRDDXSPAAREADSRWI GELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDT AKYALENKLVDALASSAEIEKALTKEFGWSKTDKNYRAIS YYDYALKTPADTGDSIGVVFANGAIXDGEETQGNVGGDTT AAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA RAAGKPVVVSXGGXAASGGYWISTPANYIVANPSTLTGSI GIFGVITTVENSLDSIGVHTDGVSTSPLADVSITRALPPE AQLXXQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVW TGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYV Description (1)  Crystal structure of Escherichia coli Signal peptide peptidase (SppA), SeMet crystals Functional site 1) chain A residue 209 type ACT_SITE sequence K description Proton donor/acceptor => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 209 type ACT_SITE sequence K description Proton donor/acceptor => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 3) chain C residue 209 type ACT_SITE sequence K description Proton donor/acceptor => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 4) chain D residue 209 type ACT_SITE sequence K description Proton donor/acceptor => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 5) chain A residue 409 type ACT_SITE sequence S description Nucleophile source Swiss-Prot : SWS_FT_FI2 6) chain B residue 409 type ACT_SITE sequence S description Nucleophile source Swiss-Prot : SWS_FT_FI2 7) chain C residue 409 type ACT_SITE sequence S description Nucleophile source Swiss-Prot : SWS_FT_FI2 8) chain D residue 409 type ACT_SITE sequence S description Nucleophile source Swiss-Prot : SWS_FT_FI2

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