eF-site ID 3bdx-ABC PDB Code 3bdx Chain A, B, C click to enlarge Title Crystal structure of the unstable and highly fibrillogenic Pro7Ser mutant of the Recombinant variable domain 6AJL2 Classification IMMUNE SYSTEM Compound Amyloid lambda 6 light chain variable region PIP (fragment) Source Homo sapiens (Human) (Q96JD1_HUMAN) Sequence A:  NFMLTQSHSVSESPGKTVTISCTRSSGSIASNYVQWYQQR PGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISG LKTEDEADYYCQSYDSSNHVVFGGGTKLTVL B:  NFMLTQSHSVSESPGKTVTISCTRSSGSIASNYVQWYQQR PGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISG LKTEDEADYYCQSYDSSNHVVFGGGTKLTVL C:  NFMLTQSHSVSESPGKTVTISCTRSSGSIASNYVQWYQQR PGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISG LKTEDEADYYCQSYDSSNHVVFGGGTKLTVL Description Functional site 1) chain A residue 101 type sequence V description BINDING SITE FOR RESIDUE ACT A 401 source : AC1 2) chain A residue 102 type sequence F description BINDING SITE FOR RESIDUE ACT A 401 source : AC1 3) chain B residue 45 type sequence P description BINDING SITE FOR RESIDUE ACT A 401 source : AC1 4) chain B residue 47 type sequence T description BINDING SITE FOR RESIDUE ACT A 401 source : AC1 5) chain A residue 45 type sequence P description BINDING SITE FOR RESIDUE ACT A 402 source : AC2 6) chain A residue 46 type sequence T description BINDING SITE FOR RESIDUE ACT A 402 source : AC2 7) chain A residue 47 type sequence T description BINDING SITE FOR RESIDUE ACT A 402 source : AC2 8) chain B residue 102 type sequence F description BINDING SITE FOR RESIDUE ACT A 402 source : AC2 9) chain A residue 98 type sequence N description BINDING SITE FOR RESIDUE ACT B 403 source : AC3 10) chain B residue 33 type sequence Y description BINDING SITE FOR RESIDUE ACT B 403 source : AC3 11) chain B residue 35 type sequence Q description BINDING SITE FOR RESIDUE ACT B 403 source : AC3 12) chain B residue 94 type sequence Y description BINDING SITE FOR RESIDUE ACT B 403 source : AC3 13) chain A residue 99 type sequence H description BINDING SITE FOR RESIDUE ACT A 404 source : AC4 14) chain B residue 50 type sequence Y description BINDING SITE FOR RESIDUE ACT A 404 source : AC4 15) chain C residue 55 type sequence R description BINDING SITE FOR RESIDUE ACT A 404 source : AC4 16) chain C residue 57 type sequence S description BINDING SITE FOR RESIDUE ACT A 404 source : AC4 17) chain C residue 66 type sequence S description BINDING SITE FOR RESIDUE ACT C 405 source : AC5 18) chain C residue 68 type sequence D description BINDING SITE FOR RESIDUE ACT C 405 source : AC5 19) chain C residue 75 type sequence S description BINDING SITE FOR RESIDUE ACT C 405 source : AC5 20) chain A residue 98 type sequence N description BINDING SITE FOR RESIDUE MES B 601 source : AC6 21) chain B residue 32 type sequence N description BINDING SITE FOR RESIDUE MES B 601 source : AC6 22) chain B residue 33 type sequence Y description BINDING SITE FOR RESIDUE MES B 601 source : AC6 23) chain B residue 94 type sequence Y description BINDING SITE FOR RESIDUE MES B 601 source : AC6 24) chain B residue 98 type sequence N description BINDING SITE FOR RESIDUE MES B 601 source : AC6 25) chain A residue 30 type sequence A description BINDING SITE FOR RESIDUE GOL A 501 source : AC7 26) chain A residue 31 type sequence S description BINDING SITE FOR RESIDUE GOL A 501 source : AC7 27) chain C residue 38 type sequence Q description BINDING SITE FOR RESIDUE GOL C 502 source : AC8 28) chain C residue 60 type sequence P description BINDING SITE FOR RESIDUE GOL C 502 source : AC8 29) chain C residue 62 type sequence R description BINDING SITE FOR RESIDUE GOL C 502 source : AC8 30) chain C residue 84 type sequence E description BINDING SITE FOR RESIDUE GOL C 502 source : AC8 31) chain C residue 85 type sequence D description BINDING SITE FOR RESIDUE GOL C 502 source : AC8 32) chain A residue 9 type sequence S description BINDING SITE FOR RESIDUE GOL A 503 source : AC9 33) chain A residue 90 type sequence Y description BINDING SITE FOR RESIDUE GOL A 503 source : AC9 34) chain A residue 104 type sequence G description BINDING SITE FOR RESIDUE GOL A 503 source : AC9 35) chain A residue 105 type sequence G description BINDING SITE FOR RESIDUE GOL A 503 source : AC9 36) chain A residue 107 type sequence K description BINDING SITE FOR RESIDUE GOL A 503 source : AC9 37) chain B residue 42 type sequence G description BINDING SITE FOR RESIDUE GOL A 503 source : AC9 38) chain B residue 30 type sequence A description BINDING SITE FOR RESIDUE GOL B 504 source : BC1 39) chain C residue 69 type sequence S description BINDING SITE FOR RESIDUE GOL B 504 source : BC1

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