eF-site ID 3bar-A PDB Code 3bar Chain A click to enlarge Title Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-azido-UMP Classification LYASE Compound Orotidine 5'-phosphate decarboxylase Source Plasmodium falciparum (Q8T6J6_PLAFA) Sequence A:  GSMGFKVKLEKRRNAINTCLCIGLDPDEKDIENFMKNEKE NNYNNIKKNLKEKYINNVSIKKDILLKAPDNIIREEKSEE FFYFFNHFCFYIINETNKYALTFKMNFAFYIPYGSVGIDV LKNVFDYLYELNIPTILDMKINDIGNTVKNYRKFIFEYLK SDSCTVNIYMGTNMLKDICYDEEKNKYYSAFVLVKTTNPD SAIFQKNLSLDNKQAYVIMAQEALNMSSYLNLEQNNEFIG FVVGANSYDEMNYIRTYFPNCYILSPGIGAQNGDLHKTLT NGYHKSYEKILINIGRAITKNPYPQKAAQMYYDQINAILK QNM Description Functional site 1) chain A residue 23 type sequence D description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 2) chain A residue 102 type sequence K description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 3) chain A residue 104 type sequence N description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 4) chain A residue 136 type sequence D description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 5) chain A residue 138 type sequence K description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 6) chain A residue 194 type sequence T description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 7) chain A residue 195 type sequence T description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 8) chain A residue 264 type sequence P description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 9) chain A residue 269 type sequence Q description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 10) chain A residue 293 type sequence G description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 11) chain A residue 294 type sequence R description BINDING SITE FOR RESIDUE U5P A 3000 source : AC1 12) chain A residue 141 type sequence D description BINDING SITE FOR RESIDUE U5P B 3000 source : AC2 13) chain A residue 145 type sequence T description BINDING SITE FOR RESIDUE U5P B 3000 source : AC2 14) chain A residue 133-146 type prosite sequence TILDMKINDIGNTV description OMPDECASE Orotidine 5'-phosphate decarboxylase active site. TIlDmKinDIGnTV source prosite : PS00156

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