eF-site ID 3b0r-B PDB Code 3b0r Chain B click to enlarge Title Human PPAR gamma ligand binding dmain complexed with GW9662 in a covalent bonded form Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGDKSPFVI YDMNSLMMGEDKIKEVAIRIFQGCQFRSVEAVQEITEYAK SIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLI SEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDD SDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQL KLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKHPL LQEIY Description Functional site 1) chain B residue 282 type sequence F description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 2) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 3) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 4) chain B residue 289 type sequence S description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 5) chain B residue 323 type sequence H description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 6) chain B residue 326 type sequence I description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 7) chain B residue 327 type sequence Y description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 8) chain B residue 330 type sequence L description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 9) chain B residue 363 type sequence F description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 10) chain B residue 449 type sequence H description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 11) chain B residue 453 type sequence L description BINDING SITE FOR RESIDUE GW9 B 1 source : AC2 12) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 13) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 14) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 15) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 16) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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