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eF-site ID
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3ay4-ABC |
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PDB Code
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3ay4 |
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Chain
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A, B, C |
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click to enlarge
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Title
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Crystal structure of nonfucosylated Fc complexed with bis-glycosylated soluble form of Fc gamma receptor IIIa |
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Classification
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IMMUNE SYSTEM |
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Compound
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Ig gamma-1 chain C region |
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Source
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(FCG3A_HUMAN) |
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Sequence
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A: |
CPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSH
EDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTV
LHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQV
YTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPE
NNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVM
HEALHNHYTQKSLSL
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| B: |
CPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSH
EDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTV
LHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQV
YTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPE
NNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVM
HEALHNHYTQKSLSLS
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| C: |
LPKAVVFLEPQWYRVLEKDSVTLKCQQWFHNESLISSQAS
SYFIDAATVDDSGEYRCQTQLSTLSDPVQLEVHIGWLLLQ
APRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFH
HNSDFYIPKATLKDSGSYFCRGLVGSKNVSSETVQITITQ
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Description
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Functional site
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1)
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chain |
C |
| residue |
74 |
| type |
CARBOHYD |
| sequence |
Q
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
C |
| residue |
169 |
| type |
CARBOHYD |
| sequence |
Q
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
A |
| residue |
423-429 |
| type |
prosite |
| sequence |
FSCSVMH
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| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FSCSVMH
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| source |
prosite : PS00290
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4)
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chain |
C |
| residue |
45 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21768335, ECO:0000269|PubMed:22023369
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| source |
Swiss-Prot : SWS_FT_FI2
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5)
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chain |
C |
| residue |
162 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21768335, ECO:0000269|PubMed:22023369
|
| source |
Swiss-Prot : SWS_FT_FI2
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