eF-site ID 3avs-A PDB Code 3avs Chain A click to enlarge Title Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II) Classification OXIDOREDUCTASE Compound Lysine-specific demethylase 6A Source Homo sapiens (Human) (KDM6A_HUMAN) Sequence A:  SVSIYPSSAEVLKACRNNSSILLDKCPPPRPPSSPYPPLP KDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRG LAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENW DPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLRPFKT IKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSH VGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGP GDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLY EANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV GPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNI KVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHG RTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDC ARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPP Description Functional site 1) chain A residue 1137 type sequence K description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 2) chain A residue 1143 type sequence T description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 3) chain A residue 1146 type sequence H description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 4) chain A residue 1148 type sequence E description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 5) chain A residue 1154 type sequence S description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 6) chain A residue 1156 type sequence N description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 7) chain A residue 1166 type sequence W description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 8) chain A residue 1226 type sequence H description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 9) chain A residue 1238 type sequence A description BINDING SITE FOR RESIDUE OGA A 1501 source : AC1 10) chain A residue 1331 type sequence C description BINDING SITE FOR RESIDUE ZN A 1502 source : AC2 11) chain A residue 1334 type sequence C description BINDING SITE FOR RESIDUE ZN A 1502 source : AC2 12) chain A residue 1358 type sequence C description BINDING SITE FOR RESIDUE ZN A 1502 source : AC2 13) chain A residue 1361 type sequence C description BINDING SITE FOR RESIDUE ZN A 1502 source : AC2 14) chain A residue 1146 type sequence H description BINDING SITE FOR RESIDUE NI A 1503 source : AC3 15) chain A residue 1148 type sequence E description BINDING SITE FOR RESIDUE NI A 1503 source : AC3 16) chain A residue 1226 type sequence H description BINDING SITE FOR RESIDUE NI A 1503 source : AC3 17) chain A residue 1320 type sequence H description BINDING SITE FOR RESIDUE NI A 1504 source : AC4 18) chain A residue 1101 type sequence H description BINDING SITE FOR RESIDUE NI A 1505 source : AC5 19) chain A residue 1027 type sequence R description BINDING SITE FOR RESIDUE CL A 1506 source : AC6 20) chain A residue 1121 type sequence H description BINDING SITE FOR RESIDUE EDO A 1507 source : AC7 21) chain A residue 1253 type sequence V description BINDING SITE FOR RESIDUE EDO A 1508 source : AC8 22) chain A residue 1257 type sequence E description BINDING SITE FOR RESIDUE EDO A 1508 source : AC8 23) chain A residue 1295 type sequence C description BINDING SITE FOR RESIDUE EDO A 1508 source : AC8 24) chain A residue 1298 type sequence R description BINDING SITE FOR RESIDUE EDO A 1508 source : AC8 25) chain A residue 928 type sequence Y description BINDING SITE FOR RESIDUE EDO A 1509 source : AC9 26) chain A residue 1030 type sequence T description BINDING SITE FOR RESIDUE EDO A 1510 source : BC1 27) chain A residue 1034 type sequence K description BINDING SITE FOR RESIDUE EDO A 1510 source : BC1 28) chain A residue 1035 type sequence Y description BINDING SITE FOR RESIDUE EDO A 1510 source : BC1 29) chain A residue 1083 type sequence K description BINDING SITE FOR RESIDUE EDO A 1510 source : BC1 30) chain A residue 1213 type sequence R description BINDING SITE FOR RESIDUE EDO A 1511 source : BC2 31) chain A residue 1214 type sequence P description BINDING SITE FOR RESIDUE EDO A 1511 source : BC2 32) chain A residue 946 type sequence E description BINDING SITE FOR RESIDUE EDO A 1512 source : BC3 33) chain A residue 981 type sequence L description BINDING SITE FOR RESIDUE EDO A 1513 source : BC4 34) chain A residue 982 type sequence G description BINDING SITE FOR RESIDUE EDO A 1513 source : BC4 35) chain A residue 985 type sequence S description BINDING SITE FOR RESIDUE EDO A 1513 source : BC4 36) chain A residue 1159 type sequence I description BINDING SITE FOR RESIDUE EDO A 1513 source : BC4 37) chain A residue 985 type sequence S description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 38) chain A residue 986 type sequence T description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 39) chain A residue 1039 type sequence Q description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 40) chain A residue 1160 type sequence G description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 41) chain A residue 1161 type sequence P description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 42) chain A residue 1234 type sequence C description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 43) chain A residue 1235 type sequence N description BINDING SITE FOR RESIDUE EDO A 1514 source : BC5 44) chain A residue 889 type sequence I description BINDING SITE FOR RESIDUE EDO A 1515 source : BC6 45) chain A residue 891 type sequence P description BINDING SITE FOR RESIDUE EDO A 1515 source : BC6 46) chain A residue 971 type sequence R description BINDING SITE FOR RESIDUE EDO A 1515 source : BC6 47) chain A residue 1108 type sequence A description BINDING SITE FOR RESIDUE EDO A 1516 source : BC7 48) chain A residue 1111 type sequence R description BINDING SITE FOR RESIDUE EDO A 1516 source : BC7 49) chain A residue 1114 type sequence S description BINDING SITE FOR RESIDUE EDO A 1516 source : BC7 50) chain A residue 1115 type sequence A description BINDING SITE FOR RESIDUE EDO A 1516 source : BC7 51) chain A residue 1146 type BINDING sequence H description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1 52) chain A residue 1148 type BINDING sequence E description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1 53) chain A residue 1226 type BINDING sequence H description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1 54) chain A residue 1331 type BINDING sequence C description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1 55) chain A residue 1334 type BINDING sequence C description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1 56) chain A residue 1358 type BINDING sequence C description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1 57) chain A residue 1361 type BINDING sequence C description BINDING => ECO:0000269|PubMed:22002947 source Swiss-Prot : SWS_FT_FI1

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