|
|
eF-site ID
|
3avr-B |
|
PDB Code
|
3avr |
|
Chain
|
B |
|
click to enlarge
|
|
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Title
|
Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II) |
|
Classification
|
OXIDOREDUCTASE/STRUCTURAL PROTEIN |
|
Compound
|
Lysine-specific demethylase 6A |
|
Source
|
Homo sapiens (Human) (3AVR) |
|
|
Sequence
|
B: |
RKQLATKAARXSAPATG
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
27 |
| type |
|
| sequence |
X
|
| description |
BINDING SITE FOR RESIDUE OGA A 1501
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
23 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-methyllysine; alternate => ECO:0000269|PubMed:17194708
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
3)
|
chain |
B |
| residue |
26 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Citrulline => ECO:0000269|PubMed:16567635
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
4)
|
chain |
B |
| residue |
27 |
| type |
MOD_RES |
| sequence |
X
|
| description |
N6-methyllysine; alternate => ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
5)
|
chain |
B |
| residue |
17 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Citrulline; alternate => ECO:0000269|PubMed:15345777, ECO:0000269|PubMed:16497732, ECO:0000269|PubMed:16567635
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
B |
| residue |
18 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:17194708
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
B |
| residue |
18 |
| type |
LIPID |
| sequence |
K
|
| description |
N6-decanoyllysine => ECO:0000269|PubMed:35939806
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
8)
|
chain |
B |
| residue |
28 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15684425, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
|