eF-site ID 3ao1-B PDB Code 3ao1 Chain B click to enlarge Title Fragment-based approach to the design of ligands targeting a novel site in HIV-1 integrase Classification VIRAL PROTEIN/TRANSFERASE INHIBITOR Compound POL polyprotein Source Human immunodeficiency virus 1 (Q72498_9HIV1) Sequence B:  SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQE TAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACDWAGIK QEGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHK RKGGIGGYSAGERIVDIIATDI Description Functional site 1) chain B residue 131 type sequence D description BINDING SITE FOR RESIDUE CD A 1003 source : AC1 2) chain B residue 131 type sequence D description BINDING SITE FOR RESIDUE CD A 1004 source : AC2 3) chain B residue 106 type sequence G description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 4) chain B residue 107 type sequence R description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 5) chain B residue 109 type sequence P description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 6) chain B residue 109 type sequence P description BINDING SITE FOR RESIDUE BZX A 214 source : AC5 7) chain B residue 65 type sequence C description BINDING SITE FOR RESIDUE CD B 1001 source : AC6 8) chain B residue 92 type sequence E description BINDING SITE FOR RESIDUE CD B 1001 source : AC6 9) chain B residue 116 type sequence D description BINDING SITE FOR RESIDUE CD B 1001 source : AC6 10) chain B residue 65 type sequence C description BINDING SITE FOR RESIDUE CD B 1002 source : AC7 11) chain B residue 67 type sequence H description BINDING SITE FOR RESIDUE CD B 1002 source : AC7 12) chain B residue 92 type sequence E description BINDING SITE FOR RESIDUE CD B 1002 source : AC7 13) chain B residue 83 type sequence Y description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 14) chain B residue 184 type sequence N description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 15) chain B residue 185 type sequence H description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 16) chain B residue 197 type sequence G description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 17) chain B residue 198 type sequence E description BINDING SITE FOR RESIDUE BZX B 1 source : AC8

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