eF-site ID 3ao1-A PDB Code 3ao1 Chain A click to enlarge Title Fragment-based approach to the design of ligands targeting a novel site in HIV-1 integrase Classification VIRAL PROTEIN/TRANSFERASE INHIBITOR Compound POL polyprotein Source Human immunodeficiency virus 1 (Q72498_9HIV1) Sequence A:  SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQE TAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACDWAGIK QEDGIPSMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHK RKGGIGGYSAGERIVDIIATD Description Functional site 1) chain A residue 65 type sequence C description BINDING SITE FOR RESIDUE CD A 1003 source : AC1 2) chain A residue 67 type sequence H description BINDING SITE FOR RESIDUE CD A 1003 source : AC1 3) chain A residue 92 type sequence E description BINDING SITE FOR RESIDUE CD A 1003 source : AC1 4) chain A residue 65 type sequence C description BINDING SITE FOR RESIDUE CD A 1004 source : AC2 5) chain A residue 92 type sequence E description BINDING SITE FOR RESIDUE CD A 1004 source : AC2 6) chain A residue 116 type sequence D description BINDING SITE FOR RESIDUE CD A 1004 source : AC2 7) chain A residue 69 type sequence E description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 8) chain A residue 71 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 9) chain A residue 166 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 10) chain A residue 170 type sequence E description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 11) chain A residue 171 type sequence H description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 12) chain A residue 172 type sequence L description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 13) chain A residue 187 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 14) chain A residue 83 type sequence Y description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 15) chain A residue 184 type sequence N description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 16) chain A residue 185 type sequence H description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 17) chain A residue 197 type sequence G description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 18) chain A residue 201 type sequence V description BINDING SITE FOR RESIDUE BZX A 213 source : AC4 19) chain A residue 70 type sequence G description BINDING SITE FOR RESIDUE BZX A 214 source : AC5 20) chain A residue 185 type sequence H description BINDING SITE FOR RESIDUE BZX A 214 source : AC5 21) chain A residue 106 type sequence G description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 22) chain A residue 107 type sequence R description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 23) chain A residue 108 type sequence W description BINDING SITE FOR RESIDUE BZX B 1 source : AC8 24) chain A residue 109 type sequence P description BINDING SITE FOR RESIDUE BZX B 1 source : AC8

Display surface Download Links