eF-site ID 3anm-A PDB Code 3anm Chain A click to enlarge Title Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with 5-phenylpyridin-2-ylmethylphosphonic acid Classification OXIDOREDUCTASE Compound 1-deoxy-D-xylulose 5-phosphate reductoisomerase Source null (DXR_ECOLI) Sequence A:  GKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVT RMVEQCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLS GQQAACDMAALEDVDQVMAAIVGAAGLLPTLAAIRAGKTI LLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLAT MTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFN ASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPI AHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKL AMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAALN LSVLEKMDMREPQCVDDVLSVDANAREVARKEVMRLASSA Description Functional site 1) chain A residue 184 type sequence G description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 2) chain A residue 185 type sequence S description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 3) chain A residue 208 type sequence H description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 4) chain A residue 210 type sequence N description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 5) chain A residue 211 type sequence W description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 6) chain A residue 221 type sequence S description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 7) chain A residue 226 type sequence N description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 8) chain A residue 227 type sequence K description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 9) chain A residue 253 type sequence S description BINDING SITE FOR RESIDUE SYD A 800 source : AC1 10) chain A residue 7 type sequence G description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 11) chain A residue 9 type sequence T description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 12) chain A residue 10 type sequence G description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 13) chain A residue 11 type sequence S description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 14) chain A residue 12 type sequence I description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 15) chain A residue 34 type sequence A description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 16) chain A residue 35 type sequence G description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 17) chain A residue 36 type sequence K description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 18) chain A residue 37 type sequence N description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 19) chain A residue 56 type sequence D description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 20) chain A residue 99 type sequence A description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 21) chain A residue 100 type sequence I description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 22) chain A residue 101 type sequence V description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 23) chain A residue 104 type sequence A description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 24) chain A residue 122 type sequence A description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 25) chain A residue 123 type sequence N description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 26) chain A residue 124 type sequence K description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 27) chain A residue 149 type sequence D description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 28) chain A residue 275 type sequence M description BINDING SITE FOR RESIDUE NDP A 410 source : AC2 29) chain A residue 125 type BINDING sequence E description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 30) chain A residue 150 type BINDING sequence S description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 31) chain A residue 185 type BINDING sequence S description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 32) chain A residue 208 type BINDING sequence H description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 33) chain A residue 214 type BINDING sequence G description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 34) chain A residue 221 type BINDING sequence S description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 35) chain A residue 226 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 36) chain A residue 227 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 37) chain A residue 11 type BINDING sequence S description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 38) chain A residue 12 type BINDING sequence I description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 39) chain A residue 35 type BINDING sequence G description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 40) chain A residue 36 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 41) chain A residue 37 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 42) chain A residue 123 type BINDING sequence N description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 43) chain A residue 124 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 44) chain A residue 9 type BINDING sequence T description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 45) chain A residue 10 type BINDING sequence G description BINDING => ECO:0000269|PubMed:15567415, ECO:0007744|PDB:1Q0Q source Swiss-Prot : SWS_FT_FI1 46) chain A residue 149 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12621040, ECO:0007744|PDB:1ONO, ECO:0007744|PDB:1ONP source Swiss-Prot : SWS_FT_FI2 47) chain A residue 151 type BINDING sequence E description BINDING => ECO:0000269|PubMed:12621040, ECO:0007744|PDB:1ONO, ECO:0007744|PDB:1ONP source Swiss-Prot : SWS_FT_FI2 48) chain A residue 230 type BINDING sequence E description BINDING => ECO:0000269|PubMed:12621040, ECO:0007744|PDB:1ONO, ECO:0007744|PDB:1ONP source Swiss-Prot : SWS_FT_FI2

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