eF-site ID 3adu-B PDB Code 3adu Chain B click to enlarge Title Human PPARgamma ligand-binding domain in complex with 5-methoxy-indole acetate Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKSPFVIY DMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSV EAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTML ASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEF AVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHV QLLQVIKKTETSLHPLLQEIY Description Functional site 1) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE MYI B 3 source : AC3 2) chain B residue 326 type sequence I description BINDING SITE FOR RESIDUE MYI B 3 source : AC3 3) chain B residue 333 type sequence L description BINDING SITE FOR RESIDUE MYI B 3 source : AC3 4) chain B residue 342 type sequence S description BINDING SITE FOR RESIDUE MYI B 3 source : AC3 5) chain B residue 281 type sequence I description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 6) chain B residue 284 type sequence G description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 7) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 8) chain B residue 330 type sequence L description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 9) chain B residue 339 type sequence V description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 10) chain B residue 342 type sequence S description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 11) chain B residue 348 type sequence M description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 12) chain B residue 364 type sequence M description BINDING SITE FOR RESIDUE MYI B 4 source : AC4 13) chain B residue 286 type sequence Q description BINDING SITE FOR RESIDUE MYI B 5 source : AC5 14) chain B residue 289 type sequence S description BINDING SITE FOR RESIDUE MYI B 5 source : AC5 15) chain B residue 323 type sequence H description BINDING SITE FOR RESIDUE MYI B 5 source : AC5 16) chain B residue 327 type sequence Y description BINDING SITE FOR RESIDUE MYI B 5 source : AC5 17) chain B residue 449 type sequence H description BINDING SITE FOR RESIDUE MYI B 5 source : AC5 18) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 19) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 20) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 21) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 22) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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