eF-site ID 3ads-B PDB Code 3ads Chain B click to enlarge Title Human PPARgamma ligand-binding domain in complex with indomethacin Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPFVI YDMNSLMMGEDKIKFKKEVAIRIFQGCQFRSVEAVQEITE YAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDG VLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALE LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKK TETHPLLQEIY Description Functional site 1) chain B residue 281 type sequence I description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 2) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 3) chain B residue 289 type sequence S description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 4) chain B residue 292 type sequence A description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 5) chain B residue 326 type sequence I description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 6) chain B residue 330 type sequence L description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 7) chain B residue 333 type sequence L description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 8) chain B residue 340 type sequence L description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 9) chain B residue 341 type sequence I description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 10) chain B residue 343 type sequence E description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 11) chain B residue 364 type sequence M description BINDING SITE FOR RESIDUE IMN B 3 source : AC3 12) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 13) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 14) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 15) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 16) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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