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eF-site ID
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3a5w-ABCDEFGHIJ |
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PDB Code
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3a5w |
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Chain
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A, B, C, D, E, F, G, H, I, J |
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click to enlarge
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Title
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Peroxiredoxin (wild type) from Aeropyrum pernix K1 (reduced form) |
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Classification
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OXIDOREDUCTASE |
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Compound
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Probable peroxiredoxin |
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Source
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Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (TDXH_AERPE) |
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Sequence
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A: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHATHT
VRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKALKLG
DSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARMESGQ
YRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLLYEE
A
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| B: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA
THTVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKAL
KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL
YEEA
|
| C: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA
THTVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKAL
KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL
YEEA
|
| D: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA
THTVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKAL
KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL
YEEA
|
| E: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAATH
TVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKALKL
GDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARMESG
QYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLLYE
EA
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| F: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA
THTVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKAL
KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL
YEEA
|
| G: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAATH
TVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKALKL
GDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARMESG
QYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLLYE
EA
|
| H: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA
THTVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKAL
KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL
YEE
|
| I: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA
THTVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKAL
KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL
YEEA
|
| J: |
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFS
HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS
HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAATH
TVRGVFIVDARGVIRTMLYYPMELGRLVDEILRIVKALKL
GDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARMESG
QYRCLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLLYE
E
|
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Description
|
(1) |
Probable peroxiredoxin (E.C.1.11.1.15)
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
J |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
C |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
D |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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6)
|
chain |
E |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
F |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
G |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
H |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
I |
| residue |
50 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
A |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
12)
|
chain |
J |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
13)
|
chain |
B |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
14)
|
chain |
C |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
15)
|
chain |
D |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
16)
|
chain |
E |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
17)
|
chain |
F |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
18)
|
chain |
G |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
19)
|
chain |
H |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
20)
|
chain |
I |
| residue |
126 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|