eF-site ID 2znv-D PDB Code 2znv Chain D click to enlarge Title Crystal structure of human AMSH-LP DUB domain in complex with Lys63-linked ubiquitin dimer Classification HYDROLASE/Signaling Protein Compound AMSH-like protease Source Homo sapiens (Human) (UBIQ_MOUSE) Sequence D:  GLRCVVLPEDLCHKFLQLAESNTVRGIATCGILCGKLTHN EFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLG WIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHK DTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVL VKDIKIIVLDLR Description Functional site 1) chain D residue 362 type sequence H description BINDING SITE FOR RESIDUE ZN D 2 source : AC2 2) chain D residue 402 type sequence C description BINDING SITE FOR RESIDUE ZN D 2 source : AC2 3) chain D residue 408 type sequence H description BINDING SITE FOR RESIDUE ZN D 2 source : AC2 4) chain D residue 410 type sequence H description BINDING SITE FOR RESIDUE ZN D 2 source : AC2 5) chain D residue 359 type sequence V description BINDING SITE FOR RESIDUE EDO D 3 source : AC5 6) chain D residue 405 type sequence K description BINDING SITE FOR RESIDUE EDO D 3 source : AC5 7) chain D residue 406 type sequence G description BINDING SITE FOR RESIDUE EDO D 3 source : AC5 8) chain D residue 407 type sequence F description BINDING SITE FOR RESIDUE EDO D 3 source : AC5 9) chain D residue 349 type SITE sequence H description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 10) chain D residue 360 type SITE sequence D description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 11) chain D residue 362 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2 12) chain D residue 402 type SITE sequence C description Essential for function source Swiss-Prot : SWS_FT_FI2 13) chain D residue 408 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2 14) chain D residue 410 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2

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