eF-site ID 2znv-A
PDB Code 2znv
Chain A

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Title Crystal structure of human AMSH-LP DUB domain in complex with Lys63-linked ubiquitin dimer
Classification HYDROLASE/Signaling Protein
Compound AMSH-like protease
Source Homo sapiens (Human) (UBIQ_MOUSE)
Sequence A:  GLRCVVLPEDLCHKFLQLAESNTVRGIATCGILCGKLTHN
EFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLG
WIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHK
DTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVL
VKDIKIIVLDLR
Description


Functional site

1) chain A
residue 362
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 1
source : AC1

2) chain A
residue 402
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1
source : AC1

3) chain A
residue 408
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 1
source : AC1

4) chain A
residue 410
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 1
source : AC1

5) chain A
residue 362
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 2
source : AC3

6) chain A
residue 366
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 2
source : AC3

7) chain A
residue 400
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 2
source : AC3

8) chain A
residue 408
type SITE
sequence H
description Essential for function
source Swiss-Prot : SWS_FT_FI2

9) chain A
residue 410
type SITE
sequence H
description Essential for function
source Swiss-Prot : SWS_FT_FI2


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