eF-site ID 2zno-AB PDB Code 2zno Chain A, B click to enlarge Title Human PPAR gamma ligand binding domain in complex with a synthetic agonist TIPP703 Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence A:  QLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTT DKSPFVIYDMNSLMMGEDKIQEQSKEVAIRIFQGCQFRSV EAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTML ASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEF AVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHV QLLQVIKKTETDMSLHPLLQEIYKDL B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGDKSPFVI YDMNSLMMGEDKIKFSKEVAIRIFQGCQFRSVEAVQEITE YAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDG VLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALE LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKK TETHPLLQEIY Description Functional site 1) chain A residue 255 type sequence L description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 2) chain A residue 280 type sequence R description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 3) chain A residue 281 type sequence I description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 4) chain A residue 282 type sequence F description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 5) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 6) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 7) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 8) chain A residue 323 type sequence H description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 9) chain A residue 341 type sequence I description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 10) chain A residue 348 type sequence M description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 11) chain A residue 364 type sequence M description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 12) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 13) chain A residue 473 type sequence Y description BINDING SITE FOR RESIDUE S44 A 901 source : AC1 14) chain B residue 255 type sequence L description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 15) chain B residue 280 type sequence R description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 16) chain B residue 282 type sequence F description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 17) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 18) chain B residue 286 type sequence Q description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 19) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 20) chain B residue 289 type sequence S description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 21) chain B residue 323 type sequence H description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 22) chain B residue 327 type sequence Y description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 23) chain B residue 330 type sequence L description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 24) chain B residue 341 type sequence I description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 25) chain B residue 363 type sequence F description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 26) chain B residue 364 type sequence M description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 27) chain B residue 449 type sequence H description BINDING SITE FOR RESIDUE S44 B 902 source : AC2 28) chain A residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 29) chain A residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 30) chain A residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 31) chain A residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 32) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 33) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 34) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 35) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 36) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2 37) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links