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eF-site ID
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2zkh-HL |
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PDB Code
|
2zkh |
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Chain
|
H, L |
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click to enlarge
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Title
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Human thrombopoietin neutralizing antibody TN1 FAB |
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Classification
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IMMUNE SYSTEM |
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Compound
|
Monoclonal TN1 FAB light chain |
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Source
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(2ZKH) |
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Sequence
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H: |
EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQS
PEKGLEWVAEIRSKVNNHAIHYAESVKGRFTVSRDDSKSS
VYLQMNSLRAEDTGIYYCSGWSFLYWGQGTLVTVSAAKTT
PPSVYPLAPSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVH
TFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASST
KVDKKIVPR
|
| L: |
QVVLTQSPGIMSASPGEKVTITCSASSSVSYMYWFQQKPG
TSPKLWIYSTSNLASGVPARFRGSGSGTSYSLTISRMEAE
DAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIFPPS
SEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLN
SWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTS
TSPIVKSFNR
|
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Description
|
|
Functional site
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|
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1)
|
chain |
L |
| residue |
191-197 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
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