|
|
eF-site ID
|
2zk2-B |
|
PDB Code
|
2zk2 |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with glutathion conjugated 15-deoxy-delta12,14-prostaglandin J2 |
|
Classification
|
TRANSCRIPTION |
|
Compound
|
Peroxisome proliferator-activated receptor gamma |
|
Source
|
Homo sapiens (Human) (PPARG_HUMAN) |
|
|
Sequence
|
B: |
ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSP
FVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQ
FRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEII
YTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEP
KFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPI
EDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIV
TEHVQLLQVIKKTETHPLLQEIY
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
286 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
323 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
449 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
473 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
B |
| residue |
224 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|