eF-site ID 2zjw-A PDB Code 2zjw Chain A click to enlarge Title Crystal structure of human CK2 alpha complexed with Ellagic acid Classification TRANSFERASE Compound Casein kinase II subunit alpha Source Homo sapiens (Human) (CSK21_HUMAN) Sequence A:  MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQ LVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKR EIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPH NVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGP ELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKR WERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAME HPYFYTVVKDQA Description Functional site 1) chain A residue 45 type sequence L description BINDING SITE FOR RESIDUE REF A 336 source : AC1 2) chain A residue 53 type sequence V description BINDING SITE FOR RESIDUE REF A 336 source : AC1 3) chain A residue 66 type sequence V description BINDING SITE FOR RESIDUE REF A 336 source : AC1 4) chain A residue 68 type sequence K description BINDING SITE FOR RESIDUE REF A 336 source : AC1 5) chain A residue 81 type sequence E description BINDING SITE FOR RESIDUE REF A 336 source : AC1 6) chain A residue 95 type sequence I description BINDING SITE FOR RESIDUE REF A 336 source : AC1 7) chain A residue 113 type sequence F description BINDING SITE FOR RESIDUE REF A 336 source : AC1 8) chain A residue 175 type sequence D description BINDING SITE FOR RESIDUE REF A 336 source : AC1 9) chain A residue 45-68 type prosite sequence LGRGKYSEVFEAINITNNEKVVVK description PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK source prosite : PS00107 10) chain A residue 152-164 type prosite sequence IMHRDVKPHNVMI description PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI source prosite : PS00108 11) chain A residue 156 type ACT_SITE sequence D description Proton acceptor source Swiss-Prot : SWS_FT_FI1 12) chain A residue 45 type BINDING sequence L description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 13) chain A residue 68 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links